Protalix Biotherapeutics Ltd. - Plant protein-based medical treatment
Protalix has developed a unique technology for producing plant cell cultures for the large-scale production of complex human therapeutic proteins.
The company's platform technology is designed to produce the entire range of human protein therapeutics, with a particular emphasis on monoclonal antibodies.
Protalix's flagship product is a protein used in the treatment of Gaucher's disease, a severe genetic illness that primarily affects Jews of Eastern European extraction.
The estimated cost of production of human therapeutic proteins with Protalix's system is substantially lower than in mammalian cell-based systems Protalix is currently negotiating with several bio-pharmaceutical companies interested in obtaining a license for joint development and marketing of this and other therapeutic proteins.
Protalix's closed, industrial scale system utilizes plant cell cultures under controlled, sterile, environmentally-safe conditions. The company's facility has ISO 9002 approval for its production process and holds a U.S. and European patent for its bioreactor and platform technology. Additional patent applications for the company's products and technologies have been submitted.
Nanomotion Ltd. - Tiny Solid-State Piezoelectric Motors
Nanomotion develops, manufactures and markets tiny solid-state ceramic servo motors and positioning systems. These ultrasonic motors are exceptionally fast, powerful and precise. They offer high resolution and low settling time, coupled with a dynamic range of velocity and force. They have no moving parts, no extrinsic or intrinsic magnetic fields and, in stall, produce no electrostatic fields.
They are currently employed in the semiconductor industry to operate microscopic systems for robotics and control systems in a vacuum and for a diversified range of applications from semiconductors to biomedical, metrology to data storage.
Recently, Nanomotion began implementing solutions for moving optical lenses in cellular telephones and modern cameras.
Nanomotion Ltd. was founded in 1992 after two-year incubation at Israel's prestigious Technion Institute of Science. Its multidisciplinary R&D department includes mechanical engineers, electrical engineers, chemists, and physicists as well as software engineers.
About 90% of Nanomotion's sales are to customers outside of Israel, about half through its US subsidiary. Nanomotion Inc. also sells through distributors and directly to customers in Europe and the Asia-Pacific region, primarily Japan.
Margan Business Development Ltd. - Early Building and Facility Damage Detection
Margan's unique Quantitative Acoustic Emission (QAE) Non Destructive Inspection (NDI) technology analyses acoustical signatures for the early detection of invisible damage to buildings, storage facilities and manufacturing plants. This technology eliminates the need for invasive examination and costly production delays.
Margan has successfully applied this technology to a variety of structures, including pressure vessels, reactors, pipelines, industrial buildings after trauma, bridges and tunnels.
Since 1999, the company has focused on the inspection of High Energy Piping (HEP) and other critical plant components in power stations. QAE NDI is capable of inspecting the HEP during operation, locating flaws, identifying their type, quantitatively assessing their stress intensity (danger level), and monitoring the dynamics of their development, all this at less than 20% of the current cost of NDI.
Margan launched QAE NDI in the U.S in 200 and a monitoring station in 2002. Since then, it has inspected dozens of lines and numerous monitoring systems have been installed and are now served by Margan's American subsidiary. The company is currently preparing to penetrate the European market.
Pegasus Technologies Ltd. - Handwriting Input For Portable Electronics
Pegasus Technologies is a leading provider of handwriting input solutions for PCs, PDAs and cellular phones. Pegasus' revolutionary electronic pen is the world's first device that captures natural handwriting on any surface onto any computing device for storage, integration with other computerized documents and e-mailing via PC, PDA or cellular phone.
All Pegasus products are available either accessories to computing
devices or as embedded chip set solutions.
Established in 1991 to develop 3D products for the gaming and office markets, Pegasus Technologies Ltd. changed its business model in 1997 to exploit the rapidly increasing need for integrating natural handwriting into portable electronics.
Pegasus manufactures and sells a range of these ultrasound technology-based wireless products in the Asia-Pacific region, primarily in Japan.
BioView Ltd. - Medical Screening and Diagnostics
BioView develops, manufactures and supplies rapid automated imaging systems for cells in blood, urine and amniotic fluid samples, as well as biological kits and software. Their systems use machine vision to identify individual damaged cells in samples containing tens of millions of cells. They are currently used to track the efficacy of cancer treatments. However, the company also plans to apply its unique technology to the early cancer identification and early stage detection of fetal abnormalities.
Founded in Israel in 2000, BioView is a privately-owned company with on-staff biologists, software engineers and physicists develop and provide complete solutions to medical institutes and universities: from preparation kits, to scanning technology for morphological and fluorescent imaging, to final report and presentation templates for physicians and lab personnel.
BioView has a marketing and sales-oriented subsidiary serving hospitals and research laboratories in the United States and is assisted by a network of distributors in Europe.
BioView is a public company traded in Tel-Aviv stock exchange.